索引超出了数组界限。 文章摘要
|本期目录/Table of Contents|

[1]郑瑗瑗,赵晨露,赵文霞.细胞铁死亡在肝纤维化进展中的作用机制[J].国际消化病杂志,2024,03:146-149.
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细胞铁死亡在肝纤维化进展中的作用机制(PDF)

《国际消化病杂志》[ISSN:1673-534X/CN:31-1953/R]

期数:
2024年03期
页码:
146-149
栏目:
综述
出版日期:
2024-06-25

文章信息/Info

Title:
-
作者:
郑瑗瑗; 赵晨露; 赵文霞
450000 河南郑州， 河南中医药大学第一附属医院肝胆脾胃科
Author(s):
-
关键词:
铁死亡; 肝纤维化; 肝星状细胞; 肝细胞; 库普弗细胞; 肝窦内皮细胞
Keywords:
-
分类号:
-
DOI:
10.3969/j.issn.1673-534X.2024.03.002
文献标识码:
-
摘要:
肝纤维化的发病机制是慢性肝损伤刺激肝星状细胞活化，引起细胞外基质过度沉积。铁死亡是近年来受到关注的一种新型细胞死亡方式，表现为铁依赖性活性氧产生，导致细胞膜发生致命性脂质过氧化。研究表明细胞铁死亡与肝纤维化密切相关。该文从构成肝脏微环境的肝星状细胞、肝细胞、库普弗细胞和肝窦内皮细胞这4个方面综述细胞铁死亡在肝纤维化进展中的作用机制，为肝纤维化的临床治疗提供思路。
Abstract:
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参考文献/References

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备注/Memo

备注/Memo:
基金项目：国家自然科学基金面上项目（81473651）
更新日期/Last Update: 2024-06-25