|本期目录/Table of Contents|

[1]徐国厚,钱晓兰,钱波,等.上海男性非体力劳动者脂肪肝的检出率及易感因素分析[J].国际消化病杂志,2024,03:154-159.
 XU Guohou,HUANG Haixia,QU Mingyue,et al.Detection rate and susceptibility factors of fatty liver in male non-manual workers in Shanghai[J].International Journal of Digestive Disease,2024,03:154-159.
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上海男性非体力劳动者脂肪肝的检出率及易感因素分析(PDF)

《国际消化病杂志》[ISSN:1673-534X/CN:31-1953/R]

期数:
2024年03期
页码:
154-159
栏目:
论著
出版日期:
2024-06-25

文章信息/Info

Title:
Detection rate and susceptibility factors of fatty liver in male non-manual workers in Shanghai
作者:
徐国厚钱晓兰钱波黄海峡田建广瞿明月
214065 江苏无锡,华东疗养院放射科(徐国厚、黄海峡、瞿明月),护理部(钱晓兰),老年病科(钱波),科教科(田建广)
Author(s):
XU Guohou HUANG Haixia QU MingyueQIAN XiaolanTIAN Jianguang
XU Guohou, HUANG Haixia, QU Mingyue. Department of Radiology, Huadong Sanatorium, Wuxi 214065, China; QIAN Xiaolan. Department of Nursing, Huadong Sanatorium, Wuxi 214065, China;QIAN Bo. Department of Geriatrics, Huadong Sanatorium, Wuxi 214065, China; TIAN Jianguang. Department of Science and Education, Huadong Sanatorium, Wuxi 214065, China
关键词:
脂肪肝非体力劳动者患病率肥胖症易感因素
Keywords:
Fatty liver Non-manual workers Prevalence Obesity Susceptible factors
分类号:
-
DOI:
10.3969/j.issn.1673-534X.2024.03.004
文献标识码:
-
摘要:
目的分析上海男性非体力劳动者的脂肪肝患病情况及其易感因素,为该人群的脂肪肝防治提供参考依据。方法选择2023年1月至2023年12月华东疗养院健康管理中心体检者中的16959名男性非体力劳动者作为研究对象,收集其基本资料,以及实验室和影像学检查结果。采用单因素和多因素分析探讨脂肪肝的易感因素。采用ROC曲线分析相关指标对男性非体力劳动者患脂肪肝的预测价值。结果上海男性非体力劳动者的脂肪肝检出率为55.97%,并且其随着年龄增长呈升高趋势,60岁以上者稍有下降。体育运动是脂肪肝的保护因素,年龄、肥胖症、吸烟、饮酒、饮食不均衡、高血压、糖尿病、高三酰甘油(TG)血症、高尿酸血症(HUA)和空腹血糖受损(IFG)均是上海男性非体力劳动者患脂肪肝的易感因素。饮食不均衡、糖尿病对上海男性非体力劳动者患脂肪肝的预测价值均较高,而IFG的预测价值最高。结论上海男性非体力劳动者的脂肪肝检出率较高,并随着年龄增长而升高,体育运动是其患脂肪肝的保护因素,年龄、肥胖症、吸烟、饮酒、饮食不均衡、高血压、糖尿病、高TG血症、HUA和IFG均是其患脂肪肝的易感因素,其中饮食不均衡、糖尿病和IFG对该人群患脂肪肝的预测价值均较高。
Abstract:
Objective? This paper aims to analyze the prevalence and susceptibility factors of fatty liver among male non-manual workers in Shanghai, and provide reference for the prevention and treatment of fatty liver in this population. Methods? A total of 16 959 male non-manual workers who underwent physical examinations at the Health Management Center of Huadong Sanatorium from January 2023 to December 2023 were selected as the research subjects, and their basic data, laboratory indicators, and imaging examination results were collected. Single factor and multivariate analysis were conducted to explore the susceptibility factors of fatty liver. The ROC curve was used to analyze the predictive value of various indicators for fatty liver disease. Results? The detection rate of fatty liver in male non-manual workers in Shanghai is 55.97%, and it shows an increasing trend with age, with a slight decrease in those over 60 years old. Physical exercise is a protective factor for fatty liver. Age, obesity, smoking, drinking, unbalanced diet,

参考文献/References

1 中华医学会肝病学分会脂肪肝和酒精性肝病学组, 中国医师协会脂肪性肝病专家委员会. 酒精性肝病防治指南(2018更新版)[J].中华肝脏病杂志, 2018, 26(3): 188-194.
2Ding L, Oligschlaeger Y, Shiri-Sverdlov R, et al. Nonalcoholic fatty liver disease[J]. Handb Exp Pharmacol, 2022, 270: 233-269.
3 中国肺癌早诊早治专家组, 中国西部肺癌研究协作中心. 中国肺癌低剂量CT筛查指南(2023年版)[J]. 中国肺癌杂志, 2023, 26(1): 1-9.
4 李蒙, 张丽, 张泽伟, 等. 胸部低剂量CT肺癌筛查在检出其他常见慢性非传染性疾病的价值[J]. 中华放射学杂志, 2022, 56(2):217-220.
5 娄莹, 马文君, 王子君, 等. 中国高血压临床实践指南计划书[J].中华心血管病杂志, 2022, 50(7): 671-675.
6 中华中医药学会糖尿病基层防治专家指导委员会. 国家糖尿病基层中医防治管理指南(2022)[J]. 中华糖尿病杂志, 2023, 15(2):100-117.
7Stewart J, McCallin T, Martinez J, et al. Hyperlipidemia[J]. Pediatr Rev, 2020, 41(8): 393-402.
8 李艳, 任俊红. 超声诊断颈动脉粥样硬化斑块的方法和规范化应用[J]. 中华全科医师杂志, 2022, 21(2): 105-108.
9 中国民族卫生协会重症代谢疾病分会, 高尿酸血症相关疾病诊疗多学科共识专家组. 中国高尿酸血症相关疾病诊疗多学科专家共识(2023年版)[J]. 中国实用内科杂志, 2023, 43(6): 461-480.
10 Saiman Y, Duarte-Rojo A, Rinella ME. Fatty liver disease: Diagnosis and stratification[J]. Annu Rev Med, 2022, 73: 529-544.
11 Goldshtein I, Chodick G, Kochba I, et al. Identification and characterization of nonalcoholic fatty liver disease[J]. Clin Gastroenterol Hepatol, 2020, 18(8): 1887-1889.
12 Erard D, Villeret F, Chouik Y, et al. Dual alcohol and metabolic-related liver disease: Results from a population of liver transplant patients[J]. Liver Int, 2024, 44(2): 422-432.
13 仇燕, 钱波, 仲怀琴. BMI正常人群幽门螺杆菌感染与非酒精性脂肪性肝病的相关性分析[J]. 国际消化病杂志, 2023, 43(3): 154-158, 164.
14 Jeon S, Carr R. Alcohol effects on hepatic lipid metabolism[J]. J Lipid Res, 2020, 61(4): 470-479.
15 Chen B, Sun L, Zeng G, et al. Gut bacteria alleviate smoking-related NASH by degrading gut nicotine[J]. Nature, 2022, 610(7932): 562-568.
16 Pirola CJ, Sookoian S. Non-alcoholic fatty liver disease mediates the effect of obesity on arterial hypertension[J]. Liver Int, 2023, 43(10):2167-2176.
17 Lee CH, Lui DT, Lam KS. Non-alcoholic fatty liver disease and type 2 diabetes: An update[J]. J Diabetes Investig, 2022, 13(6): 930-940.
18 陈兆斌, 黄丽媛, 王炳元, 等. 代谢相关脂肪性肝病与2型糖尿病的关系及共病机制研究进展[J]. 临床肝胆病杂志, 2023, 39(10):2454-2459.
19 Man S, Deng Y, Ma Y, et al. Prevalence of liver steatosis and fibrosis in the general population and various high-risk populations: A nationwide study with 5.7 million adults in China[J]. Gastroenterology, 2023, 165(4): 1025-1040.
20 侯淑惠, 邓晓玲, 次白, 等. 尿酸参与代谢相关性脂肪性肝病发生、发展的分子机制研究进展[J]. 肝脏, 2023, 28(8): 990-994.
21 Li Y, Chen C, Lu L, et al. Cadmium exposure in young adulthood is associated with risk of nonalcoholic fatty liver disease in midlife[J]. Dig Dis Sci, 2022, 67(2): 689-696.
22 Balakrishnan M, Rehm J. A public health perspective on mitigating the global burden of chronic liver disease[J]. Hepatology, 2024, 79(2): 451-459.

备注/Memo

备注/Memo:
基金项目:上海市加强公共卫生体系建设三年行动计划(2023-2025)(GWVI-11.1-28、GWVI-8);华东疗养院第十一届院级课题青年项目(2024013)
更新日期/Last Update: 2024-06-25