索引超出了数组界限。 文章摘要
|本期目录/Table of Contents|

[1]王晓晗,韩丰,沈亮,等.A20在胆管结扎所致肝纤维化小鼠中的表达及作用机制研究[J].国际消化病杂志,2021,04:303-307.
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A20在胆管结扎所致肝纤维化小鼠中的表达及作用机制研究(PDF)

《国际消化病杂志》[ISSN:1673-534X/CN:31-1953/R]

期数:
2021年04期
页码:
303-307
栏目:
短篇论著
出版日期:
2021-10-01

文章信息/Info

Title:
-
作者:
王晓晗韩丰沈亮陈云清沈月玉高晨侯震涛冀子中范竹萍
314001嘉兴学院附属医院消化内科(王晓晗、韩丰、高晨、侯震涛、冀子中),心血管内科(沈亮),感染科(陈云清、沈月玉);200001上海交通大学医学院附属仁济医院消化内科(范竹萍)
Author(s):
-
关键词:
A20胆管结扎肝纤维化炎性反应
Keywords:
-
分类号:
-
DOI:
10.3969/j.issn.1673-534X.2021.04.016
文献标识码:
-
摘要:
目的研究胆管结扎(BDL)所致肝纤维化模型小鼠肝脏中A20及炎性因子的表达情况,在细胞水平探讨A20的作用机制。
Abstract:
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参考文献/References

[1]Roehlen N, Crouchet E, Baumert TF. Liver fibrosis: mechanistic concepts and therapeutic perspectives[J]. Cells, 2020, 9(4): 875.
[2]Dewidar B, Meyer C, Dooley S, et al. TGF-β in hepatic stellate cell activation and liver fibrogenesis-updated 2019[J]. Cells, 2019, 8(11): 1419.
[3]Wang X, Ai L, Xu Q, et al. A20 Attenuates liver fibrosis in NAFLD and inhibits inflammation responses[J]. Inflammation, 2017, 40(3): 840-848.
[4]Yang S, Wu Y, Wang D, et al. Establishment of an experimental method for detecting circulating miRNAs in BDL mice[J]. Clin Exp Med, 2012, 12(4): 273-277.
[5]Priem D, van Loo G, Bertrand MJM. A20 and cell death-driven inflammation[J]. Trends Immunol, 2020, 41(5): 421-435.
[6]Da Silva CG, Cervantes JR, Studer P, et al. A20--an omnipotent protein in the liver: Prometheus myth resolved?〖KG-*2〗[J]. Adv Exp Med Bio, 2014, 809: 117-139.
[7]Ramsey HE, Da Silva CG, Longo CR, et al. A20 protects mice from lethal liver ischemia/reperfusion injury by increasing peroxisome proliferator-activated receptor-alpha expression[J]. Liver Transpl, 2009, 15(11): 1613-1621.
[8]Man K, Ng KT, Lee TK, et al. Fty720 attenuates hepatic ischemia-reperfusion injury in normal and cirrhotic livers[J]. Am J Transplant, 2005, 5(1): 40-49.
[9]Sun J, Sun L, Zhang N, et al. A20 is up-regulated in primary mouse hepatocytes subjected to hypoxia and reperfusion[J]. Cell Biochem Funct, 2012, 30(8): 683-686.
10 Arvelo MB, Cooper JT, Longo C, et al. A20 protects mice from D-galactosamine/lipopolysaccharide acute toxic lethal hepatitis[J]. Hepatology, 2002, 35(3): 535-543.
11 Longo CR, Patel VI, Shrikhande GV, et al. A20 protects mice from lethal radical hepatectomy by promoting hepatocyte proliferation via a P21waf1-dependent mechanism[J]. Hepatology, 2005, 42(1): 156-164.
12 Xu MQ, Wang W, Xue L, et al. NF-Kappab activation and zinc finger protein A20 expression in mature dendritic cells derived from liver allografts undergoing acute rejection[J]. World J Gastroenterol, 2003, 9(6): 1296-1301.
13 Xu MQ, Yan LN, Gou XH, et al. Zinc finger protein A20 promotes regeneration of small-for-size liver allograft and suppresses rejection and results in a longer survival in recipient rats[J]. J Surg Res, 2009, 152(1): 35-45.
14 Yang J, Xu MQ, Yan LN, et al. Zinc finger protein A20 protects rats against chronic liver allograft dysfunction[J]. World J Gastroenterol, 2012, 18(27): 3537-3550.
15 Fan J, Chen Q, Wei L, et al. Asiatic acid ameliorates CCL4-induced liver fibrosis in rats: involvement of Nrf2/ARE, NF-κB/IκBα, and JAK1/STAT3 signaling pathways[J]. Drug Des Devel Ther, 2018, 12: 3595-3605.
16 Wang R, Wang J, Song F, et al. Tanshinol ameliorates CCl4-induced liver fibrosis in rats through the regulation of Nrf2/HO-1 and NF-κB/IκBα signaling pathway[J]. Drug Des Devel Ther, 2018, 12: 1281-1292.

备注/Memo

备注/Memo:
基金项目:浙江省医药卫生科技计划项目(2018KY798);嘉兴市第一医院优秀青年基金(2018-GG-10);嘉兴市第一医院市级医学重点学科(2019-zc-08)
更新日期/Last Update: 2021-10-01