索引超出了数组界限。 文章摘要
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[1]周萌,段超勤,陈志荣.腺病毒介导NAMPT过表达对酒精性脂肪性肝病大鼠的作用及机制研究[J].国际消化病杂志,2021,04:308-312.
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腺病毒介导NAMPT过表达对酒精性脂肪性肝病大鼠的作用及机制研究(PDF)

《国际消化病杂志》[ISSN:1673-534X/CN:31-1953/R]

期数:
2021年04期
页码:
308-312
栏目:
短篇论著
出版日期:
2021-10-01

文章信息/Info

Title:
-
作者:
周萌段超勤陈志荣
215000南京医科大学附属苏州医院消化内科
Author(s):
-
关键词:
烟酰胺磷酸核糖转移酶酒精性脂肪性肝病NF-κBTNF-α
Keywords:
-
分类号:
-
DOI:
10.3969/j.issn.1673-534X.2021.04.017
文献标识码:
-
摘要:
目的探究烟酰胺磷酸核糖转移酶(NAMPT)对酒精性脂肪性肝病(AFLD)大鼠的作用及机制。
Abstract:
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参考文献/References

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[2]Xie ZY, Xiao ZH, Wang FF. Inhibition of autophagy reverses alcohol-induced hepatic stellate cells activation through activation of Nrf2-Keap1-ARE signaling pathway[J]. Biochimie, 2018, 147(2): 55-62.
[3]Khullar M, Sharma A, Wani A, et al. Acteoside ameliorates inflammatory responses through NF-κB pathway in alcohol induced hepatic damage[J]. Int Immunopharmacol, 2019, 69: 109-117.
[4]Li XQ, Lei J, Mao LH, et al. NAMPT and NAPRT, key enzymes in NAD salvage synthesis pathway, are of negative prognostic value in colorectal cancer[J]. Front Oncol, 2019, 9: 736.
[5]Brandl L, Zhang Y, Kirstein N, et al. Targeting c-MYC through interference with NAMPT and SIRT1 and their association to oncogenic drivers in murine serrated intestinal tumorigenesis[J]. Neoplasia, 2019, 21(10): 974-988.
[6]Lin YC, Wu HC, Liao CC, et al. Secretion of one adipokine Nampt/Visfatin suppresses the inflammatory stress-induced NF-κB activity and affects Nampt-dependent cell viability in Huh-7 cells[J]. Mediators Inflamm, 2015, 2015: 392471.
[7]Chen Y, Liang Y, Hu T, et al. Endogenous Nampt upregulation is associated with diabetic nephropathy inflammatoryfibrosis through the NF-κB p65 and Sirt1 pathway; NMN alleviates diabetic nephropathy inflammatoryfibrosis by inhibiting endogenous Nampt[J]. Exp Ther Med, 2017, 14(5): 4181-4193.
[8]Han K, Zhang Y, Yang Z. Cilostazol protects rats against alcoholinduced hepatic fibrosis via suppression of TGF-β1/CTGF activation and the cAMP/Epac1 pathway[J]. Exp Ther Med, 2019, 17(3): 2381-2388.
[9]Mohan R, Jose S, Sukumaran S, et al. Curcumin-galactomannosides mitigate alcohol-induced liver damage by inhibiting oxidative stress, hepatic inflammation, and enhance bioavailability on TLR4/MMP events compared to curcumin[J]. J Biochem Mol Toxicol, 2019, 33(6): e22315.
10 Pan JH, Lim Y, Kim JH, et al. Root bark of Ulmus davidiana var. japonica restrains acute alcohol-induced hepatic steatosis onset in mice by inhibiting ROS accumulation[J]. PLoS One, 2017, 12(11): e0188381.
11 Chen Y, Manna SK, Golla S, et al. Glutathione deficiency-elicited reprogramming of hepatic metabolism protects against alcohol-induced steatosis[J]. Free Radic Biol Med, 2019, 143: 127-139.
12 Li S, Wang C, Li K, et al. NAMPT knockdown attenuates atherosclerosis and promotes reverse cholesterol transport in ApoE KO mice with high-fat-induced insulin resistance[J]. Sci Rep, 2016, 6: 26746.
13 Abu Aboud O, Chen CH, Senapedis W, et al. Dual and specific inhibition of NAMPT and PAK4 by KPT-9274 decreases kidney cancer growth[J]. Mol Cancer Ther, 2016, 15(9): 2119-2129.
14 Travelli C, Colombo G, Mola S, et al. NAMPT: A pleiotropic modulator of monocytes and macrophages[J]. Pharmacol Res, 2018, 135: 25-36.
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备注/Memo

备注/Memo:
基金项目:苏州市“科教兴卫”青年科技项目(KJXW2017032)
通信作者:陈志荣,Email: czr88188@163.com
更新日期/Last Update: 2021-10-01